ADVANCES IN NON-SURGICAL INTERVENTIONS FOR UTERINE FIBROIDS: PATIENT-CENTERED OUTCOMES AT MARDAN MEDICAL COMPLEX
DOI:
https://doi.org/10.70765/2pggs048Keywords:
Uterine fibroids, Non-surgical interventions, Uterine artery embolization, Focused ultrasound surgery, Patient outcomesAbstract
OBJECTIVE:
Uterine fibroids significantly affect the quality of life of women, with symptoms including excessive bleeding, pain, and infertility. Non-surgical interventions have emerged as effective alternatives to invasive procedures like hysterectomy.To evaluate the outcomes of non-surgical interventions for uterine fibroids, including symptom severity, fibroid size reduction, and patient satisfaction, at Mardan Medical Complex, with a focus on patient-centered outcomes.
METHOD: this study was conducted after ethical aproval at gynea b ward mardan medical complex.the study assessed demographic data, clinical characteristics, and treatment outcomes, including symptom relief and quality-of-life measures. data were statistically analyzed using descriptive and inferential methods, with significance determined at p < 0.05.
RESULT: This study analyzed data from 150 patients receiving uterine artery embolization (UAE), focused ultrasound surgery (FUS), and pharmacological therapy. UAE showed the highest symptom reduction (60%), followed by FUS (50%) and pharmacological therapy (40%). Size reduction was consistent across all modalities, with no statistically significant differences observed (p>0.05).
CONCLUSION:Non-surgical approaches such as UAE and FUS are effective and patient-centered alternatives for managing uterine fibroids. Tailored treatments are critical for optimizing patient satisfaction and clinical outcomes.
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References
1.Stewart EA, Cookson CL, Gandolfo RA, Schulze-Rath R. Epidemiology of uterine fibroids: A systematic review. BJOG. 2017;124(10):1505-12. DOI: 10.1111/1471-0528.14650.
2.Wise LA, Laughlin-Tommaso SK. Epidemiology of uterine fibroids: From menarche to menopause. Clin Obstet Gynecol. 2016;59(1):2-24. DOI: 10.1097/GRF.0000000000000164.
3.Parker WH. Etiology, symptomatology, and diagnosis of uterine myomas. Fertil Steril. 2007;87(4):725-36. DOI: 10.1016/j.fertnstert.2007.01.093.
4.Williams ARW, Bergeron C, Barlow DH. Pathogenesis and pathology of uterine leiomyomas. Hum Reprod Update. 2016;22(6):665-81. DOI: 10.1093/humupd/dmw019.
5.Donnez J, Dolmans MM. Uterine fibroid management: From the present to the future. Hum Reprod Update. 2016;22(6):665-81. DOI: 10.1093/humupd/dmw023.
6.Laughlin-Tommaso SK, Stewart EA. Non-surgical management of myomas: Efficacy of medical therapies. Clin Obstet Gynecol. 2016;59(1):78-92. DOI: 10.1097/GRF.0000000000000170.
7.Baird DD, Dunson DB. High cumulative incidence of uterine leiomyoma in black and white women: Ultrasound evidence. Am J Obstet Gynecol. 2003;188(1):100-7. DOI: 10.1067/mob.2003.99.
8.Spies JB, Allison S, Flick P. Uterine artery embolization for myomas: Comparison with hysterectomy. Obstet Gynecol. 2002;99(6):873-80. DOI: 10.1016/S0029-7844(02)01938-4.
9.Kim HS, Baik JH. Focused ultrasound surgery for uterine fibroids: A decade of clinical practice. Int J Hyperthermia. 2018;34(1):174-82. DOI: 10.1080/02656736.2018.1424532.
10.Hehenkamp WJ, Volkers NA, Donderwinkel PF, Birnie E, Ankum WM, Reekers JA. Uterine artery embolization versus hysterectomy: A comparison of quality of life outcomes. Fertil Steril. 2007;88(4):730-7. DOI: 10.1016/j.fertnstert.2006.12.024.
11.Walker WJ, Pelage JP. Uterine artery embolization: An alternative to hysterectomy. Lancet. 2002;359(9323):1863-70. DOI: 10.1016/S0140-6736(01)05627-5.
12.Spies JB, Coyne K, Guaou NG. The UFS-QOL: A validated questionnaire for measuring health-related quality of life in women with uterine fibroids. Obstet Gynecol. 2002;99(2):290-300. DOI: 10.1016/S0029-7844(01)01702-1.
13.Pron G, Mocarski E, Bennett J. Pregnancy outcomes following uterine artery embolization: Results of the Ontario UFE trial. J Obstet Gynaecol Can. 2005;27(6):561-8. DOI: 10.1016/S1701-2163(16)30890-5.
14.Kim MD, Lee M, Lee DY. Uterine fibroid embolization: Effectiveness and patient satisfaction. J Vasc Interv Radiol. 2007;18(5):671-7. DOI: 10.1016/j.jvir.2007.03.028.
15.Pron G, Mocarski E, Vanderburgh L. Uterine artery embolization for fibroids: Changes in practice and patient outcomes. J Obstet Gynaecol Can. 2011;33(9):911-8. DOI: 10.1016/S1701-2163(16)34922-9.
16.Brolmann HA, Huirne JA, van der Meulen JF. Non-invasive treatment options for uterine fibroids. Best Pract Res Clin Obstet Gynaecol. 2018;46:53-63. DOI: 10.1016/j.bpobgyn.2017.10.006.
17.Sandberg EM, Tummers FHMP, Cohen SL, van den Haak L, Dekkers OM, Twijnstra ARH. Reintervention rates after uterine-sparing interventions for fibroids: A systematic review and meta-analysis. Obstet Gynecol. 2018;132(5):1321-30. DOI: 10.1097/AOG.0000000000002967.
18.Siskin GP, Tublin ME. Long-term outcomes of uterine artery embolization. J Vasc Interv Radiol. 2001;12(9):1005-11. DOI: 10.1016/S1051-0443(07)61594-8.
19.Katsumori T, Miura H, Araki Y. Short- and mid-term outcomes of uterine artery embolization for fibroids. Radiology. 2002;224(2):401-6. DOI: 10.1148/radiol.2242011430.
20.Hindley JT, Gedroyc WM, Regan L. MRI guidance of focused ultrasound therapy of uterine fibroids: Early results. AJR Am J Roentgenol. 2004;183(6):1713-9. DOI: 10.2214/ajr.183.6.01831713.
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