Surgical Site Infections Following Orthopaedic Trauma Surgery

Authors

  • dr saad medicine Author

DOI:

https://doi.org/10.70765/21dbbj36

Keywords:

Surgical site infection, postoperative complications, diabetes, hypertension, antimicrobial strategies, perioperative management.

Abstract

Objecticve: To evaluate the impact of age, diabetes, hypertension, and surgical site infection (SSI) on postoperative complications in surgical patients.

 

Method: A retrospective analysis of surgical patients was conducted, assessing age, diabetes, hypertension, and SSI as potential risk factors for postoperative complications. Data were analyzed using statistical tests to determine significance levels.

 

Result: The study found that SSI was significantly associated with surgical complications (p<0.001), whereas age, diabetes, and hypertension did not show statistically significant associations. Younger patients (20-39 years) had a higher complication rate (24%) compared to older patients (>40 years, 12.3%), though this was not significant (p=0.101).

 

Conclusion: Surgical site infection is a critical determinant of postoperative complications, emphasizing the need for stringent infection control measures. While age, diabetes, and hypertension did not show significant associations, targeted interventions for infection prevention remain crucial. Future research should explore antimicrobial strategies and optimized perioperative care to reduce SSI-related complications.

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References

1: Premkumar A, Kolin DA, Farley KX, Wilson JM, McLawhorn AS, Cross MB, et al. Projected Economic Burden of Periprosthetic Joint Infection of the hip and knee in the United States. J Arthroplast. 2021;36(5):1484–e14893.https://doi.org/10.1016/j.arth.2020.12.005

2: Diez-Escudero, A., Hailer, N. P. (2021). The Role of Silver Coating for Arthroplasty Components. Bone Joint J. 103-B (3), 423–429. doi: 10.1302/0301-620X.103B3.BJJ-2020-1370.R1

3: van Breugel JMM, Niemeyer MJS, Houwert RM, Groenwold RHH, Leenen LPH, van Wessem KJP. Global changes in mortality rates in polytrauma patients admitted to the ICU—a systematic review. World J Emerg Surg. 2020;15(1):55.https://doi.org/10.1186/s13017-020-00330-3

4: Guest JF, Fuller GW, Griffiths B. Cohort study to characterise surgical site infections after open surgery in the UK’s National Health Service. BMJ Open. 2023;13(12):e076735.https://doi.org/10.1136/bmjopen-2023-076735

5: O’Brien WJ, Gupta K, Itani KMF. Association of postoperative infection with risk of long-term infection and mortality. JAMA Surg. 2020;155(1):61–8. doi:10.1001/jamasurg.2019.4539

6: Bone infection site targeting nanoparticle-antibiotics delivery vehicle to enhance treatment efficacy of orthopedic implant related infection 2022, Bioactive Materials.https://doi.org/10.1016/j.bioactmat.2022.02.003

7: Bacterial Biofilm Formation on Biomaterials and Approaches to Its Treatment and Prevention 2023, International Journal of Molecular Sciences. https://doi.org/10.3390/ijms241411680

8: Targeted Versus Shotgun Metagenomic Sequencing-based Detection of Microorganisms in Sonicate Fluid for Periprosthetic Joint Infection Diagnosis 2023, Clinical Infectious Diseases. https://doi.org/10.1093/cid/ciac646

9: Peel TN, Astbury S, Cheng AC, Paterson DL, Buising KL, Spelman T, Tran-Duy A, Adie S, Boyce G, McDougall C, Molnar R. Trial of vancomycin and cefazolin as surgical prophylaxis in arthroplasty. New England Journal of Medicine. 2023 Oct 19;389(16):1488-98.DOI: 10.1056/NEJMoa2301401

10: Jiao J, Zhang S, Qu X, Yue B. Recent advances in research on antibacterial metals and alloys as implant materials. Frontiers in cellular and infection microbiology. 2021 Jul 2;11:693939. https://doi.org/10.3389/fcimb.2021.693939

11: Bai, R., Peng, L., Sun, Q., Zhang, Y., Zhang, L., Wei, Y., et al. (2020). Metallic Antibacterial Surface Treatments of Dental and Orthopedic Materials. Materials (Basel) 13 (20), 4594. doi: 10.3390/ma13204594

12:Bastos, R. W., Rossato, L., Valero, C., Lagrou, K., Colombo, A. L., Goldman, G. H. (2019). Potential of Gallium as an Antifungal Agent. Front. Cell Infect. Microbiol. 9, 414. doi: 10.3389/fcimb.2019.00414

13: Bolzoni, L., Alqattan, M., Peters, L., Alshammari, Y., Yang, F. (2020). Ternary Ti Alloys Functionalised With Antibacterial Activity. Sci. Rep. 10 (1), 22201. doi: 10.1038/s41598-020-79192-3

14: Capek, J., Kubasek, J., Pinc, J., Fojt, J., Krajewski, S., Rupp, F., et al. (2021). Microstructural, Mechanical, In Vitro Corrosion and Biological Characterization of an Extruded Zn-0.8Mg-0.2Sr (Wt%) as an Absorbable Material. Mater Sci. Eng. C Mater Biol. Appl. 122:111924. doi: 10.1016/j.msec.2021.111924

15: Cochis, A., Azzimonti, B., Chiesa, R., Rimondini, L., Gasik, M. (2019). Metallurgical Gallium Additions to Titanium Alloys Demonstrate a Strong Time-Increasing Antibacterial Activity Without Any Cellular Toxicity. ACS Biomater Sci. Eng. 5 (6), 2815–2820. doi: 10.1021/acsbiomaterials.9b00147

16: Liu X, Dong Z, Li J, Feng Y, Cao G, Song X, Yang J. Factors affecting the incidence of surgical site infection after geriatric hip fracture surgery: a retrospective multicenter study. Journal of Orthopaedic Surgery and Research. 2019 Dec;14:1-9.https://doi.org/10.1186/s13018-019-1449-6

17: Li J, Zhu Y, Zhao K, Zhang J, Meng H, Jin Z, Ma J, Zhang Y. Incidence and risks for surgical site infection after closed tibial plateau fractures in adults treated by open reduction and internal fixation: a prospective study. Journal of Orthopaedic Surgery and Research. 2020 Dec;15:1-0.https://doi.org/10.1186/s13018-020-01885-2

18: Hofmann A, Gorbulev S, Guehring T, Schulz AP, Schupfner R, Raschke M, Huber-Wagner S, Rommens PM. Autologous iliac bone graft compared with biphasic hydroxyapatite and calcium sulfate cement for the treatment of bone defects in tibial plateau fractures: a prospective, randomized, open-label, multicenter study. JBJS. 2020 Feb 5;102(3):179-93.DOI: 10.2106/JBJS.19.00680

19: Calderwood MS, Anderson DJ, Bratzler DW, Dellinger EP, Garcia-Houchins S, Maragakis LL, Nyquist AC, Perkins KM, Preas MA, Saiman L, Schaffzin JK. Strategies to prevent surgical site infections in acute-care hospitals: 2022 Update. Infection Control & Hospital Epidemiology. 2023 May;44(5):695-720.DOI: https://doi.org/10.1017/ice.2023.67

20: Abe T, Komori A, Shiraishi A, Sugiyama T, Iriyama H, Kainoh T, Saitoh D. Trauma complications and in-hospital mortality: failure-to-rescue. Critical Care. 2020 Dec;24:1-3.https://doi.org/10.1186/s13054-020-02951-1

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Published

2025-03-02

How to Cite

Surgical Site Infections Following Orthopaedic Trauma Surgery. (2025). Health Sciences AUS, 4(4). https://doi.org/10.70765/21dbbj36

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